Generics and Pharmaceuticals

Home/Publications/Health/Generics and Pharmaceuticals

FDA Approves Record Number of Generic Drugs, But Do They Help Lower Drug Prices?

The Food and Drug Administration (FDA) has approved a record number of generic drugs to go to market during President Donald Trump’s tenure, but drug pricing experts say it isn’t doing much to lower drug prices for consumers overall. In an interview with Fox Business, Secretary of Health and Human Services Alex Azar said flooding the

FDA Approves Record Number of Generic Drugs, But Do They Help Lower Drug Prices?

The Food and Drug Administration (FDA) has approved a record number of generic drugs to go to market during President Donald Trump’s tenure, but drug pricing experts say it isn’t doing much to lower drug prices for consumers overall. In an interview with Fox Business, Secretary of Health and Human Services Alex Azar said flooding the

A Civic Duty To Improve Access To Generic Pharmaceuticals

Introductory note: The origins of Civica Rx were discussed in a previous Health Affairs Blog post, which also addressed whether the then-unnamed company should manufacture or purchase generic drugs. This post focuses on the unique governing role that three philanthropic organizations have as investors and founding board members in this first-of-its-kind venture, which is focused on

The Other U.S. Prescription Drug Problem

Last week, drugmaker Novartis issued a recall of generic versions of the popular heartburn medication Zantac. The Food and Drug Administration recently announced that the drug's active ingredient, ranitidine, had been contaminated with a carcinogen known as NDMA. On Monday, CVS pulled Zantac and its generics from its shelves; Walgreens had already stopped selling the drug earlier. This

Elements of green chemistry

The chemical sciences has a sustainability problem. Chemical production is expected to double by 2030, according to a recent UN report, but quite how this will be done without costing the Earth is still an unanswered question. At the recent International Union of Pure and Applied Chemistry’s congress in Paris, the ‘father of green chemistry’

2019-08-19T08:33:37-06:00Tags: |

Puerto Rico pharma chiefs: Investors prefer quality, sustainability

Puerto Rico should stop giving so much importance to the island’s tax advantages to attract investors and instead focus more on sustainability and quality at a time when the supply chain factor also increases in importance. That is the consensus of industry experts who attended the Puerto Rico Manufacturers Association Convention over the weekend. Newly

2019-08-02T07:19:54-06:00Tags: |

How can the pharma industry turn its sustainability ambitions into action?

The last few weeks have reiterated the critical importance of sustainability action. From Extinction Rebellion and the overwhelmingly positive response the Committee on Climate Change’s call for net zero emission targets by 2050, to the UN’s report on biodiversity, to the pharma-specific crisis around opioids and prosecutions in the US; the issues are high profile,

2019-07-22T06:53:04-06:00Tags: |

Bottle X: Exposing Impurities in the Generic Drug Business

In June 2013, the U.S. Food and Drug Administration tapped Altaf Lal, an American of Indian origin with sterling public-health credentials, to solve what appeared to be a diplomacy problem. The FDA's relations with Indian regulators were in tatters, one month after India's largest drug company, Ranbaxy, pleaded guilty to seven felonies related to falsifying quality

Does Medicine Really Expire?

Ever since 1979, the U.S. Food and Drug Administration (FDA) has required that pharmaceutical companies put expiration dates on prescription and over-the-counter medicines. That doesn't mean your bottle of ibuprofen will go bad in the same way as, say, an expired carton of milk. The date that you see printed on a pill bottle is

2019-06-18T02:51:48-06:00Tags: |

Prescription for Poverty

New Oxfam research shows that four pharmaceutical corporations—Abbott, Johnson & Johnson, Merck & CO (MSD), and Pfizer—systematically stash their profits in overseas tax havens. They appear to deprive developing countries of more than $100 million every year—money that is urgently needed to meet the health needs of people in these countries—while vastly overcharging for their

2019-06-16T14:52:07-06:00Tags: |

Collusion over Drug Prices: Will Generic Manufacturers Pay?

A lawsuit filed by a group of 44 U.S. states against 20 generic drug makers alleging collusion and price-fixing has revealed how existing market-based, competitive mechanisms fail to protect consumers, according to experts. The complaint, filed in the U.S. District Court in Connecticut, says that drug companies have since 2012 discreetly engaged with each other on price

How Some Generic Drugs Could Do More Harm Than Good

For the 16 years that Dr. Brian Westerberg, a Canadian surgeon, worked volunteer missions at the Mulago National Referral Hospital in Kampala, Uganda, scarcity was the norm. The patients usually exceeded the 1,500 allotted beds. Running water was once cut off when the debt-ridden hospital was unable to pay its bills. On some of his

Foul play with generic drugs threatens American lives

This is becoming the year of the health care “hot potato,” as various players in the market battle over who is the villain. The Senate Finance Committee kicked off 2019 with hearings aimed at getting to the root of soaring prescription drug prices and identifying bad actors. Suggested solutions ranged from banning price spreading to reforming rebate programs. Yet

A single-dose antidote may help prevent fentanyl overdoses

Synthetic opioids outlast current antidotes. A nanoparticle-based alternative could fix that. A newly developed single-dose opioid antidote lasts several days, a study in mice shows. If the results can be duplicated in humans, the treatment may one day help prevent overdoses from deadly drugs like fentanyl. Normally, a dose of the opioid antidote naloxone passes

2019-04-04T08:19:50-06:00Tags: |

How antibiotics change human microbiome diversity long-term

A single course of antibiotics can change the composition of oral and gut microbiomes for at least a year, according to a modelling study by UCL researchers. Moreover, this change leads to a decrease in the number and types of microbes found in the gut, but an increase in the diversity of the oral microbiome.

2019-03-26T07:50:36-06:00Tags: |

Pharmaceutical abuse sent more than 350,000 people to the ER in 2016

The misuse of prescription drugs and over-the-counter medications resulted in an estimated 358,000 trips to U.S. emergency departments in 2016 — and almost half of those cases involved young people ages 15 to 34, according to a new study based on a national public health surveillance system. The analysis, reported online March 6 in the

2019-03-18T10:58:33-06:00Tags: |

Injectable pharmaceutical aims to accelerate bone healing

WEST LAFAYETTE, Ind. – Every person in the U.S. will experience, on average, two broken bones in their lifetime. It is expected that more than 6.3 million bones will be broken in the U.S. this year, according to the National Institutes of Health. Average recovery time for a young, healthy adult with a broken arm is six to

2019-03-12T11:27:52-06:00Tags: |

Do price spikes on some generic drugs indicate problems in the market?

A new USC study reports that sudden price spikes for some generic drugs — such as the recently reported increases of a decades-old generic heart medication and an antibiotic — are becoming more common. The study from the USC Schaeffer Center for Health Policy & Economics, published in the October issue of Health Affairs, shows

2019-03-07T07:48:35-06:00Tags: |

Pharmacists can substitute branded drugs with generics

The Prime Minister's office has asked the Drug Technical Advisory Board (DTAB) to move amendments to the Drugs & Cosmetics Act, 1945 that will allow pharmacists to substitute doctor's prescription of branded drugs with generic medicines. Following suggestions, the Drug Controller General of India confirmed that in the initial phase, only the Jan Aushadhi Kendras

2019-03-07T07:40:41-06:00Tags: |