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Brush your teeth — postpone Alzheimer’s

You don't only avoid holes in your teeth by keeping good oral hygiene, researchers at the University of Bergen have discovered a clear connection between gum disease and Alzheimer´s disease. The researchers have determined that gum disease (gingivitis) plays a decisive role in whether a person developes Alzheimer´s or not. "We discovered DNA-based proof that

2019-06-05T19:37:46-06:00Tags: |

Penn Medicine treats two cancer patients with gene-editing tool CRISPR

Clinicians at the University of Pennsylvania have treated two cancer patients with CRISPR, a gene-editing technology that enables precise modifications to DNA. The patients were treated as part of a recently launched U.S. CRISPR study at the Abramson Cancer Center, a Penn Medicine spokesperson confirmed Tuesday. One patient has multiple myeloma, a cancer that forms

2019-04-17T06:53:36-06:00Tags: |

Penn Med researchers find potential treatment for pancreatic tumors

A new Penn Medicine study found a treatment that shrinks pancreatic tumors in most patients in an early phase clinical trial. Researchers of the Abramson Cancer Center conducted a clinical trial where patients with untreated pancreatic cancer received standard chemotherapy treatments and an experimental antibody targeting CD40 proteins.The clinical trial saw pancreatic tumors shrink in

2019-04-15T07:07:34-06:00Tags: |

Protein Levels in the Eye a Potential Predictor of (Future) Alzheimer’s Disease

Low levels of amyloid-β and tau proteins, biomarkers of Alzheimer's disease (AD), in eye fluid were significantly associated with low cognitive scores, according to a new study published in the Journal of Alzheimer's Disease. Led by researchers at Boston Medical Center, the study is the first to connect these known AD protein biomarkers in the

2019-03-27T08:15:07-06:00Tags: |

Breakthrough shines light on disease-fighting protein

X-ray and electron microscopy techniques help unfold the story of protein chaperones. A combination of X-ray crystallography and cryo-electron microscopy (cryo-EM) assisted in a collaborative effort to obtain the highest-resolution structure of the fungal protein Hsp104, which may serve to hinder the formation of certain degenerative diseases. The team, whose members included researchers from the

2019-03-18T11:05:11-06:00Tags: |

Simply shining light on ‘dinosaur metal’ compound kills cancer cells

A new compound based on Iridium, a rare metal which landed in the Gulf of Mexico 66 M years ago, hooked onto albumin, a protein in blood, can attack the nucleus of cancerous cells when switched on by light, University of Warwick researchers have found. The treatment of cancer using light, called Photodynamic therapy, is

2019-02-06T08:15:35-06:00Tags: |

Study predicts worsening of opioid overdose crisis

A study from investigators at the Massachusetts General Hospital (MGH) Institute for Technology Assessment projects that the opioid overdose epidemic in the U.S. is likely to increase in coming years, and that measures based on restricting access to prescription opioids will have a minimal impact in reducing overdose deaths. In their report published in JAMA

2019-02-04T08:03:09-06:00Tags: |

New project launched to consolidate sustainable tuberculosis care

A new Tuberculosis Regional Eastern European and Central Asian Project, referred to as TB-REP 2.0, has been launched. This project for 2019 to 2022, building on the previous TB-REP from 2016 to 2018, will consolidate past achievements and address new and remaining challenges while ensuring continuity. In particular, it will focus on improving tuberculosis (TB)

2019-01-29T08:14:33-06:00Tags: |

Scientists find a cellular process that stops cancer before it starts

Just as plastic tips protect the ends of shoelaces and keep them from fraying when we tie them, molecular tips called telomeres protect the ends of chromosomes and keep them from fusing when cells continually divide and duplicate their DNA. But while losing the plastic tips may lead to messy laces, telomere loss may lead

2019-01-28T06:47:06-06:00Tags: |

Alleviating flashbacks by playing Tetris

A behavioural intervention procedure including the computer game Tetris could help people with post-traumatic stress disorder (PTSD) to alleviate involuntarily recurring visual memories of traumatic experiences. This is the conclusion reached by a team from Ruhr-Universität Bochum together with a researcher from the Karolinska Institutet in Sweden following a study of 20 inpatients with PTSD.

2019-01-09T06:55:13-06:00Tags: |

New material could ‘drive wound healing’

Materials are widely used to help heal wounds: Collagen sponges help treat burns and pressure sores, and scaffold-like implants are used to repair bones. However, the process of tissue repair changes over time, so scientists are developing biomaterials that interact with tissues as healing takes place. Now, Dr Ben Almquist and his team at Imperial

2019-01-07T13:31:07-06:00Tags: |

There was no relationship between obesity and poverty — until..

In 1841, Orlando Jones patented, a process that separated corn starch from kernels in what is known as wet milling. One year later, Thomas Kingford opened the first commercial wet milling plant in the States. Corn, an agricultural product dating back at least 6,000 years to the Oaxaca region of Mexico, was a natural fit

2018-12-31T06:40:02-06:00Tags: |

After naloxone, when can opioid overdose patients be safely discharged

Naloxone has saved thousands of lives. But can patients be safely discharged from the Emergency Department (ED) just an hour after they receive the medication that curtails drug overdoses? According to the St. Paul's Early Discharge Rule developed in 2000, that's how long providers should observe patients after naloxone treatment, so long as their vital

2018-12-31T14:17:00-06:00Tags: |

Potential arthritis treatment prevents cartilage breakdown

Osteoarthritis, a disease that causes severe joint pain, affects more than 20 million people in the United States. Some drug treatments can help alleviate the pain, but there are no treatments that can reverse or slow the cartilage breakdown associated with the disease. In an advance that could improve the treatment options available for osteoarthritis,

2018-12-13T08:08:04-06:00Tags: |

New Buzz about a Malaria Prevention Drug

Most malaria drugs are designed to reduce symptoms after infection. They work by blocking replication of the disease-causing parasites in human blood, but they don’t prevent infection or transmission via mosquitoes. What’s worse, the malaria parasite is developing resistance to existing drugs. “In many ways, the search for new malaria drugs has been a search

2018-12-10T07:29:10-06:00Tags: |

The vaccine saving the lives of Pacific children

This week, we marked World Pneumonia Day. Pneumonia is the single largest infectious cause of death in children worldwide, and about one-third of all childhood deaths from pneumonia are a result of the pneumococcal bacteria. Sadly, most of the deaths as a result of pneumonia occur in poor children from low and middle-income countries. These

2018-11-28T06:10:27-06:00Tags: |